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Lorenzo’s oil is 4 parts of glyceryl trioleate and 1 part glyceryl trierucate, which are the triacylglycerol forms of oleic acid and erucic acid〔http://nutrition.nutricia.com/products/lorenzos_oil〕 and are prepared from olive oil and rapeseed oil. It is used in the investigational treatment of asymptomatic patients with adrenoleukodystrophy (ALD). The oil was formulated by Augusto and Michaela Odone after their son Lorenzo was diagnosed with the disease in 1984, at the age of five, with the actual production initially developed by retired British scientist Don Suddaby (formerly of Croda International).〔(''The Telegraph'' - Lorenzo Odone obituary )〕 Suddaby and his colleague, Keith Coupland, received U.S. Patent No. 5,331,009〔(U.S. Patent 5,331,009: Pharmaceutical compositions for treating adrenoleukodystrophy ). Issued July 19, 1994.〕 for the oil. The royalties received by Augusto were paid to the Myelin Project which he and Michaela founded to further research treatments for ALD and similar disorders. The Odones and their invention obtained widespread publicity in 1992 because of the film ''Lorenzo’s Oil''. Lorenzo Odone died on May 30, 2008, at the age of 30, after suffering from aspiration pneumonia, caused by food getting stuck in his lungs.〔 〕 ==Treatment costs== Lorenzo's oil costs approximately US $440 for a month's treatment.〔(【引用サイトリンク】url=http://www.myelin.org/lorenzosoil/lorenzosoiltheoil.html )〕 In the U.S., Lorenzo's oil is currently available to only the patients taking part in a clinical trial under the direction of the Kennedy Krieger Institute. Thus, Lorenzo's oil can be obtained only through prescription by Kennedy Krieger Institute authorized physicians. A 500-ml bottle costs approximately $56.00. Some insurance companies will provide coverage for the oil, but others do not because it is still considered an experimental drug by the Food and Drug Administration (FDA).〔(【引用サイトリンク】url=http://www.myelin.org/lorenzosoil/lorenzosoiltheoil.html )〕 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Lorenzo's oil」の詳細全文を読む スポンサード リンク
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